| First | Last | Occupation | Description | Relations | Marital Status | Sexual Orientation | Gender | Age in '02 |
| Neil | Benton | Harvard University: Grad Student | tall, Slim, athletic, WASP man; dresses Ralph Lauren preppy; think John-Paul Lavoisier | Courtland & Autumn's son; Philip & Ann's brother; Roger's brother-in-law | single | unknown | male | 24 |
| Honor | Solis | private investigator | tough looking Latina; think Lisa Lo Cicero | Zac's mother | single | bisexual | female | 30 |
| Zac | Solis | middle school student | thin Latino boy | Honor's son | single | unknown | male | 11 |
| Andera | Babaracos | criminal defense attorney | woman of Greek descent with long dark curly hair; think Melina Kanakaredes | Leandro's fraternal twin sister | unknown | straight | female | 31 |
| Leandro | Babaracos | Outward Bound: instructor | stocky, yet athletic man of Greek descent, curly dark hair, square jaw; think Jeremy Sisto | Andera's fraternal twin brother | single | straight | male | 31 |
| Caillan | Bailey | criminal defense attorney | good-looking Irish-American man; wears corrective lenses; think Patrick Dempsey | Trevor & Maggie's son; Siobhan & Seamus' brother; Ginny's cousin; Eamon & Maggie's nephew; Cole’s former lover; Jillian's brother-in-law | single | queer | male | 35 |
| Jillian | Bailey | Coolidge, Hobbs, Fujito, De Vries & Assoc.: architect and partner | tall, slender dark blonde woman with subtle freckles, think McKenzie Westmore | Nathan's sister; Carter's daughter; Seamus' widow; Trevor & Maggie's daughter-in-law; Caillan & Siobhan's sister-in-law; Ginny's cousin-in-law | widowed | straight | female | 32 |
| Maggie | Bailey | homemaker; community volunteer | matronly woman of Irish descent | Trevor's wife; Caillan, Siobhan, & Seamus' mother; Brigit's sister; Eamon's brother-in-law; Ginny's aunt | married | straight | female | 57 |
| Seamus | Bailey | investment banker | dark hair; trim build; quiet, distant man of Irish descent; think Eric Mabius | Trevor & Maggie's son; Caillan & Siobhan's brother; Ginny's cousin; Eamon & Maggie's nephew; Jillian's husband | single | straight | male | 32 |
| Siobhan | Bailey | freelance journalist | slightly overweight brunette | Trevor & Maggie's daughter; Caillan & Seamus' sister; Ginny's cousin; Eamon & Maggie's niece; Jillian's sister-in-law | single | unknown | female | 33 |
| Trevor | Bailey | Santa Lorena County Judge | debonair Irish-American man | Maggie's husband; Caillan, Siobhan, & Seamus' father; Eamon & Brigit's brother-in-law; Ginny's uncle; Jillian's father-in-law | married | straight | male | 59 |
| Autumn | Benton | socialite | tall, elegant woman; think Holland Taylor | Courtland's wife; Philip, Ann, & Neil's mother; Roger's mother-in-law | married | straight | female | 59 |
| Courtland | Benton | Benton Enterprises: CEO | white haired WASP man | Autumn's husband; Philip, Ann, & Neil's father; Roger's father-in-law | married | straight | male | 61 |
| Philip | Benton | Santa Lorena District Attorney | distinguished, WASP man w/fairly dark complexion; graying at the temples; think Mark Moses | Courtland & Autumn's son; Ann & Neil's brother; Roger's brother-in-law | single | straight | male | 38 |
| Loch | Brogan | Emerson High School: student | dirty blond hair; blue eyes; think Brandon Buddy | Max' brother | single | straight | male | 15 |
| Max | Brogan | Coolidge, Hobbs, Fujito, De Vries & Assoc.: exec. asst. to Jillian De Vries; USM student | dark hair; blue eyes | Loch's brother | single | unknown | male | 19 |
| Frank | Cain | Bank of San Marcello: loan officer | dark, swarthy man of European descent; think Carmine Giovinazzo | unknown | single | straight | male | 29 |
| Carter | De Vries | DVI (De Vries International): CEO | debonair man with graying blond hair; think Alan Dale | Jillian and Nathan's father; Seamus' father-in-law | widowed | straight | male | 58 |
| Nathan | De Vries | Bank of San Marcello: loan dept. mgr. | dark blond hair, green eyes; think Jay Mohr | Jillian's brother; Carter's son | single | straight | male | 36 |
| Edward | Evans | San Marcello PD: Chief of Police | African-American man | Yolanda's father; Darius' father-in-law | married | straight | male | 57 |
| Isra | Fahmoud | University of San Marcello: student; community organizer | woman of Palestinian descent | Yasmin's cousin | single | queer | female | 23 |
| Yasmin | Fahmoud | Santa Lorena Assistant District Attorney | woman of Palestinian descent | Isra's cousin | single | straight | female | 32 |
| Latrice | Gaither | real estate agent | effervescent, sharp-tongued African-American woman; think Donna Summer | Darius' mother; Yolanda's mother-in-law | divorced | straight | female | 58 |
| Benjamin | Grondahl | University of San Marcello: professor of arachnology | mysterious and nerdy Jewish man | unknown | single | straight | male | 38 |
| Darius | Jones | criminal defense attorney | African-American man | Latrice's son; Yolanda's husband; Ed's son-in-law | married | straight | male | 40 |
| Yolanda | Jones | University Hospital: epidemiologist; San Marcello Health Dept.: Chief Medical Officer | African-American woman; think Vanessa Williams | Ed's daughter; Darius' wife; Latrice's daughter-in-law | married | straight | female | 36 |
| Marcus | Lazano | computer programmer | slim man of Italian descent; think Ryan Carnes | Vincenzo & Ramona's son; Vittorio's first cousin once removed; Veronica's stepson; Cole's lover | partnered | queer | male | 24 |
| Rhonda | Lynn | San Marcello PD: human resources director | brunette woman; think Andrea Parker | Gladys' daughter | single | straight | female | 35 |
| Ann | Manning | socialite | uptight WASP woman; think Rachel Griffiths | Roger's wife; Philip & Neil's sister; Courtland & Autumn's daughter | married | straight | female | 31 |
| Roger | Manning | attorney | ex-college football player; tall, stocky build | Ann's husband; Philip & Neil's brother-in-law; Courtland & Autumn's son-in-law; Gail's cousin; Amanda & Charles' nephew | married | straight | male | 32 |
| Adriana | Martinez | Emerson High School: student | Latina girl | Antonio & Sierra's daughter; Ignacio & Sabina's granddaughter; Diego & Leticia's sister; Benicia & Desiderio's niece | single | straight | female | 14 |
| Antonio | Martinez | University Hospital: internist | Latino man; think Esai Morales |
Sierra's husband; Leticia, Diego, & Adriana's father; Benicia & Desiderio's brother; Ignacio & Sabina's son | married | straight | male | 40 |
| Benicia | Martinez | private investigator | Latina woman; street-smart ex-gang member; think Elizabeth Rodriguez | Ignacio & Sabina's daughter; Antonio & Desiderio's sister; Sierra's sister-in-law; Leticia, Diego, & Adriana's aunt | single | bisexual | female | 31 |
| Desi | Martinez | University of San Marcello: instructor (poly sci) | Latino man; think David Fumero | Ignacio & Sabina's son; Antonio & Benicia's brother; Sierra's brother-in-law; Leticia, Diego, & Adriana's uncle | single | straight | male | 27 |
| Diego | Martinez | Emerson High School: student | Latino man | Antonio & Sierra's son; Leticia & Adriana's brother; Ignacio & Sabina's grandson; Benicia & Desiderio's nephew | single | unknown | male | 17 |
| Ignacio | Martinez | Martinez Contracting: owner; building contractor (retired) | Latino man | Antonio, Benicia, & Desiderio's father Sierra's father-in-law; Leticia, Diego, & Adriana's grandfather | married | straight | male | 60 |
| Leticia | Martinez | Emerson High School: student | Latina girl | Antonio & Sierra's daughter; Diego & Adriana's sister; Ignacio & Sabina's granddaughter; Benicia & Desiderio's niece | single | straight | female | 15 |
| Sabina | Martinez | community volunteer; retired cannery worker | Latina woman | Antonio, Benicia, & Desiderio's mother; Sierra's mother-in-law; Leticia, Diego, & Adriana's grandmother | married | straight | female | 59 |
| Sierra | Martinez | criminal defense attorney | Latina woman | Antonio's wife; Leticia, Diego, & Adriana's mother; Benicia's sister-in-law | married | straight | female | 40 |
| Hanh | Nguyen | Lotus Blossom: co-owner | immigrant woman from Vietnam | Tuan's wife; Martin, Kevin, & Luan's mother | married | straight | female | 46 |
| Kevin | Nguyen | aviator | Vietnamese-American man | Tuan & Hanh's son; Martin & Luan's brother | single | straight | male | 25 |
| Luan | Nguyen | University of San Marcello: student | tenacious young Vietnamese-American woman | Tuan & Hanh's daughter; Martin & Kevin's sister | single | straight | female | 21 |
| Martin | Nguyen | Bank of San Marcello: teller | fit, trim Vietnamese-American man; think John Cho | Tuan & Hanh's son; Kevin & Luan's brother | single | straight | male | 27 |
| Tuan | Nguyen | Lotus Blossom: co-owner | immigrant man from Vietnam | Hanh's husband; Martin, Kevin, & Luan's father | married | straight | male | 50 |
| Margaret | Park | Willow Brook Psychiatric Hospital: psychiatrist | Korean-American woman | unknown | single | straight | female | 37 |
| Samir | Patel | Bank of San Marcello: network administrator | immigrant man from India; think Ajay Naidu | unknown | single | straight | male | 27 |
| Amanda | Renwick | charity fundraising coordinator | tall, uptight WASP woman; think Jean Smart | Gail's mother; Roger's aunt | married | straight | female | 52 |
| Charles | Renwick | Benton Enterprises: CFO | distant WASP man | Gail's father; Roger's uncle | married | straight | male | 54 |
| Gail | Renwick | University Hospital: nurse | petite, fair redhead; think Laura Leighton | Amanda & Charles' daughter; Roger's cousin | single | straight | female | 28 |
| Brigit | Riley | University Hospital: OB/GYN | woman of Irish descent; think Judith Light | Eamon's wife; Ginny's mother; Maggie's sister; Trevor's sister-in-law; Caillan, Siobhan, Seamus' aunt | married | straight | female | 54 |
| Eamon | Riley | DVI: CFO; University Hospital: Board President | man of Irish descent | Brigit's husband; Ginny's father; Maggie & Trevor's brother-in-law; Caillan, Siobhan, Seamus' uncle | married | straight | male | 54 |
| Ginny | Riley | San Marcello PD: detective | tough, blonde woman; think Kelly Rutherford | Eamon & Brigit's daughter; Caillan, Siobhan, & Seamus' cousin; Trevor & Maggie's niece | single | straight | female | 32 |
| Paige | Turner | KSMO-FM: radio personality | flamboyant Jewish brunette; wears corrective lenses; think Marissa Jaret Winokur | unknown | single | straight | female | 29 |
| Cole | Washington | San Marcello PD: detective | African-American man; think Gary Dourdan | Andre & Emerald's son; Earl's brother; Marcus' lover; Caillan's former lover | partnered | queer | male | 33 |
| Earl | Washington | US Army Infantry: Staff Sergeant | African-American man | Andre & Emerald's son; Cole's brother | single | straight | male | 19 |
| Emerald | Washington | home health care worker | African-American woman | Andre's wife; Cole and Earl's mother | widowed | straight | female | 53 |
| Lillith | Williams | landlord | elderly woman | unknown | unknown | bisexual | female | 85 |
| Gladys | Lynn | unknown | matronly woman | Rhonda's mother | widowed | straight | female | 56 |
| Bruno | Corelli | Cold Forest Prison: inmate | man of Italian descent | June and Joe’s son; Leo’s brother | single | straight | male | 24 |
| Vittorio | Cuzzupe | mob operative | suave, distinguished Italian man; think Jason Gedrick | Vincenzo's cousin; Marcus' first cousin once removed | unknown | straight | male | 44 |
| Veronica | Lazano | socialite | sultry brunette; think Lara Flynn-Boyle | Amy's daughter; Vincenzo’s second wife; Marcus' stepmother | married | straight | female | 28 |
| Vincenzo | Lazano | mob kingpin in VA | dark, graying, Italian man | Marcus’ father; Veronica's husband | married | straight | male | 49 |